Base Excision Repair Pathway, The: Molecular Mechanisms And Role In Disease Development And Therapeutic Design

History of Base Excision Repair (BER) and Book Overview (David M Wilson III); Uracil DNA Glycosylases (Hans Krokan); The GO System: OGG1 and MYH (Sheila David); NEIL and NTH1 Glycosylases (Susan Wallace); Alkylative DNA Glycosylase, AAG/MPG (Leona Samson); Abasic Endonuclease, APE1 (Gianluca Tell); DNA Polymerases in BER and Pathway Choice (Samuel Wilson); End-Processing in BER (Michael Weinfeld); PARP/XRCC1 Axis in BER (Janet Hall); DNA Ligases in BER (Alan Tomkinson); Post-Translational Regulation of BER (Robert Sobol); BER in Epigenetic Programming (TDG) (Primo Schar); BER in the Immune Response (SHM, CSR) (Carol Schrader); BER in Disease Etiology (Cancer, Lupus) (Joann Sweasy); BER in TNR Expansion Disorders (Margherita Bignami); BER in Neurological Disease (Yasaku Nakabeppu); Assessing BER Capacity in the Human Population (Zachary Nagel); BER as a Prognostic Marker (Srinivasan Madhusudan); BER as a Therapeutic Target (R Stephen Lloyd); Mitochondrial BER (Nadja de Souza Pinto); BER in Aging (Tinna Stevnsner);

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• Engenharia biomédica
• Oncologia
• Biologia molecular
• Bioquímica

DNA Repair, DNA Damage, Cancer, Immunodeficiency, Neurodegeneration, Disease Susceptibility, Treatment, Inhibitor